Treatment of V. vulnificus infection includes antibiotics, aggressive wound therapy, and supportive care. Most patients who acquire the infection have at least one predisposing immunocompromising

Background. Vibrio vulnificus is a Gram-negative bacterium that can cause serious wound infections, septicaemia and gastroenteritis.1 Primary septicaemia with secondary skin and soft tissue infection usually follows ingestion of raw or poorly-cooked seafood and commonly occurs in people with underlying risk factors such as liver cirrhosis, haemochromatosis, diabetes mellitus, chronic renal

Although there is no evidence that antibiotics decrease the severity or duration of illness, they are sometimes used in severe or prolonged illnesses. Initial suspicion for V. vulnificus was high and he was started on empiric doxycycline and ceftriaxone at admission. Blood and wound cultures grew oxidase positive and comma-shaped Gram-negative rods ultimately confirmed to be V. vulnificus. Despite aggressive initial treatment, the patient developed septic shock and died.

If Vibrio vulnificus is suspected, treatment should be initiated immediately because antibiotics improve survival. Aggressive attention should be given to the wound site; for patients with wound infections, amputation of the infected limb is sometimes necessary. 2015-08-14 · Treatment strategies and clinical outcomes in patients with V. vulnificus. The time of treatment, hospitalization, antibiotics strategies, the course of treatment, and mortality seen between the survival group and the non-survival group are summarized in Table 3. V. vulnificus outbreaks commonly occur in warm climates and small, generally lethal, outbreaks occur regularly. An outbreak occurred in New Orleans after Hurricane Katrina , [18] and several lethal cases occur most years in Florida. [19] The Vibrio vulnificus (V.

V. vulnificus infections are one of the most life-threatening foodborne infectious diseases and are treated with quinolone, tetracycline, and cephalosporin

Treatment of the healthy person with mild gastroenteritis is usually supportive, with hydration as the Vibrio vulnificus infection in Hong Kong is more common in the summer months. The patient was admitted to the intensive care unit for close monitoring after.

av B Collin · 2013 · Citerat av 8 — Reported outbreaks of Vibrio parahaemolyticus have increased worldwide, Vibrio spp, Vibrio parahaemolyticus, qPCR, probe hybridization,

This poses a serious problem with respect to treatment of emergent V. vulnificus strains as they have the clear potential of becoming a multidrug-resistant pathogen.

Structurally V. vulnificus is a flagellated motile halophilic bacillus with a capsular polysaccharide (CPS), a lipopolysaccharide (LPS), and specific flagellin homologous proteins (FHPs).
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Antibiotics are necessary to eradicate V vulnificus infection. Effective antibiotics may include tetracycline, third-generation cephalosporins, and imipenem. Doxycycline (Doryx, Vibramycin, Treatment of septicemia initially involves fluid replacement for shock followed by treatment with ceftazidime 2 g intravenously every 8 h plus doxycycline 100 mg (intravenously or orally) every 12 h (Tables 49.5 and 49.9).

Antibiotics are necessary to eradicate V vulnificus infection. Effective antibiotics may include tetracycline, third-generation cephalosporins, and imipenem.
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Treatment of V. vulnificus infection includes antibiotics, aggressive wound therapy, and supportive care. Most patients who acquire the infection have at least one predisposing immunocompromising

Additionally, V Detection of V. vulnificus in pure cultures was observed over a 6-log-unit linear range of concentration (102 to 108 CFU ml−1), with a lower limit of 72 fg of genomic DNA μl of PCR mixture−1 or the equivalent of six cells. Similar sensitivity was observed in DNA extracted from mixtures of V. vulnificus and V. parahaemolyticus cells.